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Ohio State vs Indiana Prediction & Picks: College Football Week 7

By the show’s count Indiana has won 22 straight, and it is still a home underdog. Ohio State visits Bloomington, IN on Saturday, October 17 at 9:00 AM PT / 12:00 PM ET, and the Buckeyes were 3.5-point favorites with a total of 50.5 when the guys taped on October 13. Two of the three hosts took the points, and the full argument is on the College Football Picks Week 7 episode.

Ohio State vs Indiana Odds

Ohio State was a 3.5-point favorite over Indiana with a total of 50.5 when the guys taped on October 13.

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The segment opened on a simple question: with Indiana’s secondary looking like a weak spot, is this an Ohio State blowout? Colby wasn’t buying it. Then one of the guys made the case against the premise entirely, noting Indiana has won 22 straight and is somehow a dog anyway.

Ryan heard that and stayed on Ohio State. His read is that Indiana hasn’t been playing at a high level lately and isn’t covering numbers. He was upfront that recency might be talking, since he laid it with Indiana last week. Colby said a terrible roughing the passer call wiped out an Indiana interception against Nebraska and probably cost them the cover.

Colby’s real case was the Ohio State pass defense. He said the fifth-in-the-nation ranking is cooked, that Texas left yards on the field with two drops, and that Illinois moved the ball at will in the first half and finished with 462 yards at the Shoe two weeks ago. He thinks Indiana’s receivers can exploit that, and getting more than a field goal sealed it. Jeremiah Smith came up as the reason betting against Ohio State is so miserable, but Cignetti as a home dog against Ryan Day was the line that closed out the Indiana side. Ryan stuck with the Buckeyes and Ryan Day, with a detour into a Ryan Day AI image that got a laugh.

Hear the full breakdown on the College Football Picks Week 7 episode, or listen on Apple Podcasts and Spotify. Watch every game on YouTube, and download the SGPN app at sg.pn/links. See all our College Football Picks.

Listen to the full episode

More Week 7 College Football Picks

Western Kentucky vs Sam Houston State

East Carolina vs UAB

Colorado State vs Texas State

Memphis vs Tulane

Appalachian State vs Coastal Carolina

Mississippi State vs LSU

Virginia vs SMU

Florida vs Texas

Kansas vs Kansas State

Alabama vs Tennessee

Missouri vs Ole Miss

North Carolina vs Duke

Penn State vs Michigan

UNLV vs Air Force

Wisconsin vs UCLA

Oklahoma State vs Houston

Notre Dame vs BYU

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