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San Francisco 49ers vs. Seattle Seahawks – NFL – Predictions, Betting Lines, Odds and Trends

The San Francisco 49ers (0-1) are 10-point favorites when they host the Seattle Seahawks (0-0) in an NFC West matchup on Sunday, September 18, 2022 at Levi’s Stadium. The over/under is 42.5 in this game.

49ers vs. Seahawks Predictions

49ers vs. Seahawks Odds

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49ers and Seahawks: Betting Trends

  • The 49ers were 9-8-0 against the spread last season.
  • The 49ers covered every time (1-0) as a 10-point favorite or more last year.
  • In 17 49ers games last year, eight went over the total.
  • The 49ers won 57.1% of the games last season when they were the moneyline favorite (8-6).
  • The 49ers played as a moneyline favorite of -474 or shorter in just one game last season, which they won.
  • The 49ers have an 82.6% chance to win this contest based on the moneyline’s implied probability.
  • The Seahawks had nine wins in 17 games against the spread last year.
  • Last year, six of the Seahawks’ 17 games went over the point total.
  • The Seahawks were underdogs eight times last season and won three of those games.
  • The Seahawks were not a bigger underdog last season than the +358 moneyline set for this game.

Over/Under Trends

  • 49ers games finished with more than 42.5 points 11 times last season.
  • Seahawks games finished with over 42.5 points scored 11 times last year.
  • The total for this matchup is 42.5 points, 5.8 fewer than the combined scoring average of the two teams for last season.
  • These two teams combined to yield 43 points per game last season, which is 0.5 greater than the total for this matchup.
  • The over/under in this matchup is 42.5 points, 4.2 fewer than the average total in last season’s 49ers contests.
  • The average total points scored in Seahawks games last year (42.5) is 4.3 points higher than the total for this matchup.

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49ers Players to Watch

  • Deebo Samuel was the No. 16 fantasy player overall and the No. 2 fantasy WR in 2021 with 262 points (averaging 16.4 per game).
  • Jimmy Garoppolo’s 227.5 total fantasy points a season ago (an average of 15.2 per game), were good enough to place him 22nd overall and 17th among QBs.
  • Last year, Elijah Mitchell averaged 13.3 fantasy points per game on the way to 146 total fantasy points. That made him the 72nd-ranked fantasy player overall and the 24th-ranked RB.
  • George Kittle’s 2021 fantasy season saw him finish 91st overall and fourth among TEs with 125 points (8.9 per game).

Seahawks Players to Watch

  • D.K. Metcalf’s outstanding 2021 fantasy campaign saw him rack up 169.3 fantasy points (10 per game) and finish 54th overall among all players and ninth among all WRs.
  • Tyler Lockett placed 11th among WRs and 57th league-wide in fantasy standings after totaling 166.4 fantasy points (10.4 per game) last season.
  • Last year, Rashaad Penny’s 115.7 total fantasy points made him the No. 102 fantasy player and No. 31 RB. He averaged 11.6 fantasy points per game.
  • Noah Fant finished 11th among TEs and 134th overall last season in fantasy rankings. He scored 91 fantasy points (5.7 per game).

Where To Watch 49ers vs. Seahawks

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