The red hot 2-0 Indianapolis Colts head to Nashville, Tennessee on Sunday to take on their divisional rivals, the 0-2 Tennessee Titans. Can Daniel Jones keep the Colts rolling at this pace, or does #1 overall pick Cam Ward have something to say about it? Let’s take a look at this Colts at Titans preview and predictions.
The Indianapolis Colts are off to a great start on offense this season. They are the first team in the Super Bowl era to not punt through their first two games. Daniel Jones has looked like Peyton Manning and Jonathan Taylor O’s running over defenses. Their defense was stifling against the Dolphins Week 1, and steady in Week 2 against Denver.
Tennessee has been an interesting team. They’ve not gotten completely blown out in either game, but haven’t really had a chance to win either. Cam Ward looks like a rookie, and hasn’t hit 300 passing yards through two games. They are also the most penalized, and undisciplined team in the league through two weeks.
College Football Week 4 Best Bets: Upset Parlay
Indianapolis Colts at Tennessee Titans Preview and Predictions
Jonathan Taylor Longest Rush Over 17.5 Yards (-115)
Taylor has been a big part of that Colts offense with a great Week 1 against the Dolphins and an outstanding Week 2 against Denver. What should be a tough defense, Taylor gashed for 165 yards, including a 68-yard dash. In Week 1 the Titans gave up a 50-yard run to rookie RJ Harvey and a 19-yard run to JK Dobbins.
In their Week 2 match with the Rams, Kyren Williams, Blake Corum, and Puka Nacua all had at least 15-yard rushes against the Titans’ defense, including a 45-yard run by Puka. Tennessee is the fifth-worst team against the rush in 2025, and they haven’t faced anyone as good at running the ball as Taylor. One big run for a guy who gets the bulk of the work, I’m here for that.
Indianapolis Colts -4 (-110)
It’s insane to me this number is this low. Do I think Daniel Jones turns into a pumpkin at some point? Probably, but one of the best-looking offenses and a solid team through two weeks against one of the worst teams in the league. The most undisciplined, and not well coached teams. Give me the Colts all day.
It doesn’t bother me that it’s a road division spot one bit. The Titans are 3-16 against the spread since the start of 2024. It’s been seven games since they had a game end within four points, and that was to a Jacksonville team playing with a backup quarterback last year. They are on an eight-game losing streak, and there’s no reason to believe they’ll stay in this one.