San Diego Padres vs. San Francisco Giants – MLB – Predictions, Betting Lines, Odds and Trends

The San Diego Padres (87-72) and San Francisco Giants (80-79) square off on Monday at 9:40 PM ET, beginning a three-game series at PETCO Park.

The Padres are the home favorite (-272) versus the Giants (+223). The starting pitchers are Joe Musgrove (10-7) for the San Diego Padres, and John Brebbia (6-2) for the San Francisco Giants. The contest has an over/under of 7.5.

Padres vs. Giants Predictions

Padres vs. Giants Betting Odds

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Padres vs. Giants Last 10 Games Betting Performance


  • San Diego was the moneyline favorite for eight of its last 10 games, and finished 4-4 in those matchups.
  • Over their last 10 outings (all 10 of them had set totals), the Padres and their opponents combined to go over the run total three times.
  • San Diego is 4-6-0 against the spread over its past 10 games.

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  • San Francisco has been the underdog twice in the last 10 games and split those matchups 1-1.
  • In their last 10 games with a total, the Giants and their opponents have failed to hit the over five times.
  • San Francisco has six wins against the spread in its last 10 chances.

Padres vs. Giants Starting Pitcher Betting Trends

Projected starter: Joe Musgrove

  • The Padres are 14-15-0 ATS in Musgrove’s 29 starts with a set spread.
  • The Padres are 14-7 in Musgrove’s 21 starts this season with San Diego as the moneyline favorite.
  • Musgrove’s team has compiled an 18-11 record over his 29 starts.
  • Musgrove’s starts went over the run total 17 times in 29 games with a set total this season.

Projected starter: John Brebbia

  • When Brebbia starts, his team is 5-4-0 against the spread this season.
  • His team is 2-2 this season when he starts and they are the moneyline underdog.
  • In games Brebbia has started, his team is 6-3.
  • Games started by Brebbia have a 5-4-0 record at hitting the over this season.

Padres Batting Leaders

  • Manny Machado has accumulated a team-best batting average of .294, and paces the Padres in home runs (32) and runs batted in (101).
  • Machado’s home runs rank 15th in MLB and he ranks ninth in RBI in MLB.
  • Juan Soto is batting .245 with 25 doubles, two triples, 27 home runs and 134 walks.
  • Soto ranks 30th in homers and 92nd in RBI among MLB batters this season.
  • Soto heads into this matchup on a four-game hitting streak. During his last five outings he is hitting .250 with a double, a home run, a walk and an RBI.
  • Josh Bell is batting .269 with 29 doubles, three triples, 17 home runs and 78 walks.
  • Bell takes a three-game hitting streak into this game. During his last five outings he is hitting .267 with two walks and an RBI.
  • Jake Cronenworth is hitting .238 with 29 doubles, four triples, 17 home runs and 70 walks.
  • Cronenworth heads into this game on a four-game hitting streak. In his last five games he is hitting .222 with two doubles, a home run, two walks and two RBI.

Giants Batting Leaders

  • Wilmer Flores is batting .232 for San Francisco with a team-high 71 RBI.
  • Among all hitters in the majors, Flores ranks 72nd in home runs and 60th in RBI.
  • Flores takes a two-game hitting streak into this game. In his last five games he is batting .154 with a double, four walks and two RBI.
  • Thairo Estrada leads San Francisco in batting with a .261 average while slugging 14 homers and driving in 62 runs.
  • Among all MLB hitters, Estrada is 123rd in home runs and 92nd in RBI.
  • Joc Pederson is slugging .525 this season, with a team-high 23 home runs. He’s also collected 70 RBI.
  • Pederson heads into this game on a six-game hitting streak. During his last 10 outings he is batting .417 with a double, three triples, a home run, four walks and seven RBI.
  • Mike Yastrzemski has collected 101 hits this season and has an OBP of .305. He’s slugging .391 on the year.

Where To Watch Padres vs. Giants

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