The December slate brings several strong betting spots across the college basketball board. Many teams are beginning to find their rhythm as conference play approaches. That creates value in specific matchups where numbers appear misaligned. Saturday’s schedule offers six games that stand out for bettors who follow trends and situational edges. Let’s dive into Saturday’s, December 6th college basketball bets.
College Basketball Bets for Saturday, December 6th
Duke ML -110 vs Michigan State
Backing Duke on the Moneyline is a smart move even on the road because the Blue Devils remain one of the nation’s most reliable teams. Duke features strong young players like Cameron Boozer and consistent shot creation in late-game moments. Isaiah
Evans helps set the pace with steady ball movement and improved perimeter control. Duke’s depth gives them an edge in a competitive neutral-site style matchup.
Another reason to support Duke is their defensive growth early in the season. Duke has improved ball pressure and more length across the perimeter. Their roster handles physical opponents well and maintains calm when tempo shifts. That makes Michigan State’s physical approach less threatening in key stretches. Duke can close strong and protect late leads.
Seton Hall +3.5 vs Kansas State
Seton Hall is a solid underdog in this matchup because of their consistent defensive identity. The Pirates rarely give up easy drives or open perimeter looks. Their half-court execution should limit Kansas State’s transition scoring. Getting +3.5 adds support against any late-game swings. Seton Hall also performs well in close contests under pressure.
Seton Hall’s veteran presence gives them an advantage in physical games. Their experienced backcourt handles tough environments without losing composure. That steadiness is important against a Kansas State team that relies on energetic spurts. Seton Hall slows the tempo and forces opponents into longer possessions. That style favors the underdog spread.
College Basketball Bets for Saturday, December 6th
USC Upstate -1.5 vs Western Carolina
USC Upstate is well-positioned to cover because they have balanced scoring and efficient spacing. Their ball movement creates steady shot opportunities inside and out. Western Carolina struggles defending quick off-ball action, which helps Upstate create rhythm. The short line reduces risk in a tight matchup. USC Upstate’s tempo control should shape the game’s flow.
Another advantage for USC Upstate is their improved interior defense. Their rotations have tightened and they protect the rim better this season. Western Carolina can struggle when forced into contested jumpers. That places pressure on their guards to create difficult shots. Upstate’s defensive discipline supports laying the small number.
Ohio State ML -113 vs Northwestern
Taking Ohio State on the Moneyline is smart because the Buckeyes bring strong rebounding and physical play. Their frontcourt activity helps them create second-chance points in slow matchups. Northwestern struggles when overpowered on the glass. Ohio State also limits turnovers in structured half-court sets. That stability favors them in tight contests.
Ohio State’s defense should also be a difference maker. They close out shooters well and limit backdoor lanes. Northwestern relies heavily on perimeter timing to build scoring stretches. Ohio State disrupts that rhythm and forces difficult mid-range shots. Their defensive pressure supports a Moneyline position.
College Basketball Bets for Saturday, December 6th
USC -5.5 vs Washington
USC is the stronger team and matches up well with Washington’s inconsistent structure. They move the ball well and scores efficiently at all three levels. Washington can struggle containing aggressive wings and quick guards. USC’s lineup spacing forces Washington to defend deep into the shot clock. That advantage supports laying the 5.5.
Another reason to back USC is their interior athleticism. They contest shots at the rim and run the floor with purpose. Washington often falls behind against teams with steady transition pressure. USC can generate scoring runs using defense-to-offense momentum. That helps create separation and cover the spread.
Oklahoma State -2.5 vs Grand Canyon
Oklahoma State is a strong play due to their athletic defense and controlled pace. They contest drives and force opponents into late shot attempts. Grand Canyon struggles when tempo slows and possessions become heavier. Oklahoma State’s physicality gives them the advantage inside. The -2.5 number offers fair value.
Another reason to take Oklahoma State is their improved offensive spacing. They create clean shots through structured sets and off-screen movement. Grand Canyon can allow open mid-range looks when defending rotations. Oklahoma State should capitalize on these gaps throughout the game. Their balance supports covering the spread.











