Welcome to Week 10 of College Football action! Last week delivered us another outright dog and a few fun sweats! In Week 10, there are plenty of opportunities for the dogs to bark once again. Let’s dive into the College Football Week 10 lines and find our best bets underdogs to build an upset parlay.
Ole Miss was a small dog, but mighty enough to cash the +175 last week. Their in-state rivals came oh-so-close to delivering the upset over Texas at (+215). That one felt like a great bet for the majority of the day. Looking ahead to Week 10, we’ve got some exciting matchups on tap. It doesn’t start with Penn State at Ohio State, but what could have been. Vanderbilt at Texas is a strong SEC showdown. Cincinnati at Utah is the College Gameday game. Georgia and Florida face off in The World’s Largest Cocktail Party. The evening games bring us USC at Nebraska in Lincoln and Oklahoma at Tennessee in Knoxville.
Now is a good time to remind you to bet these teams individually on the moneyline, and I like to bet them with the points as well. If you did this last week, it was hugely successful. If they are good enough to pull the upset, it makes a great case for taking them with the points as well.
College Football Week 10 Best Bets: Upset Parlay
Navy (+195)
Let’s head to Denton, Texas, for an exciting AAC matchup to kick off the parlay. The Navy Midshipmen are one of just six remaining undefeated teams in the country. They’ll take on the Mean Green of the University of North Texas. North Texas brings the top-scoring offense in the country into this game. Redshirt freshman QB Drew Mestemaker has been tearing it up for the Mean Green. Where they struggle, though, is on defense. North Texas would prefer for this game to be a shootout. Exchanging possessions back and forth and trying to just outfly Navy with their air-raid attack offense.
Navy’s goal will be to slow the game down. If they can do that, they’ll control this game. Blake Horvath, the experienced Navy Senior quarterback, has been stellar rushing the ball, like any good Navy quarterback. He’s scored 12 touchdowns and had five straight games of 100+ rushing yards. Navy is fifth in the nation on third-down conversions. Slow the game down, play Midshipman ball, keep North Texas’s offense on the sidelines, and Navy will win this game and remain undefeated.
Wake Forest (+260)
It’s almost shocking that the Demon Deacons are the underdogs in this game, but we’ll take it. Wake Forest has been a fun team to follow in 2025, and they are 2-0 on the road this year. Florida State is on the struggle bus. They’ve lost nine straight ACC games and sit at just 3-4 on the season. Wake Forest is on a 4-0 run against the spread, and the underdog has won three of Florida State’s last four games.
Wake Forest has a stifling defense, ranked 26th in the nation in points per game (18.9). This Florida State team is ravaged by injuries, and Wake Forest has been able to play to their opponents’ strengths. Whether that’s keeping the game low scoring and tight like last week in a 13-12 win over SMU. Or, a shootout like their 30-29 loss to Georgia Tech in overtime. It’s the perfect combination to fade a bad Florida State team, while backing an exciting Wake Forest squad.
Cincinnati (+260)
The Cincinnati Bearcats head into Rice-Eccles Stadium in Salt Lake City, Utah, on Saturday. It’s a game with massive Big 12 Conference implications. College Gameday will even be in attendance. Cincinnati will need to bring its absolute best. Luckily for them, Heisman Trophy candidate Brendan Sorsby leads the way for the Bearcats, who are on a seven-game win streak at 7-1. Their only loss came in their first game in a nail-biter to the Nebraska Cornhuskers in a neutral-site game that was every bit of a Husker home game.
Both of these offenses are electric, and were likely in for one exciting shootout. Scott Satterfield and Brendan Sorsby are going to be the keys to putting the Bearcats over the top. Utah cruises in off a huge and easy win over the Colorado Buffaloes. If Cincinnati can catch them sleepwalking early and control the pace, they can win this game.
Navy + Wake Forest + Cincinnati Upset Parlay (+3723)
Toss these three upset winners into a parlay, and it gives you odds north of 37/1. Toss a cool $20 on it, and the payout will give you $764.64. Kick back, relax, and enjoy some barking dogs on a crisp, cool fall day.
