The NFL season is almost upon us! If you haven’t already started placing those NFL futures bets, now is as good a time as any to get started. The NFL Offensive Player of the Year award has trended towards being awarded to the best non-quarterback in recent years. Will that trend continue, and who do the odds lead us to bet on? Let’s take a look at the 2025 NFL Best Bets: Offensive Player of the Year odds, trends, and past winners.
Last year, Eagles running back Saquon Barkley grabbed the award for the first time in his career with his new team on their way to the Super Bowl LIX victory. It was the second year in a row a running back won the award, but just the third time in the last 10 years. Christian McCaffrey (2022) and Todd Gurley (2017) were the other two.
As covered in the 2025 NFL Best Bets MVP: Odds, Trends, & Past Winners, that award has been handed to a quarterback in 12 straight seasons and 17 of the last 18 years. From 2007 to 2018, a quarterback also won this award eight times. However, since Patrick Mahomes’ 2018 win of OPOTY, it’s gone to either a running back or a wide receiver despite plenty of quarterbacks who could have easily been deserving. One final note: every player who has won it since Adrian Peterson in 2012 has been on a team that’s won at least 11 games.
2025 NFL Best Bets: Offensive Player of the Year Odds, Trends, and Past Winners
2015 QB Cam Newton
2016 QB Matt Ryan
2017 RB Todd Gurley
2018 QB Patrick Mahomes
2019 WR Michael Thomas
2020 RB Derrick Henry
2021 WR Cooper Kupp
2022 WR Justin Jefferson
2023 RB Christian McCaffrey
2024 RB Saquon Barkley
2025 NFL Offensive Player of the Year Odds
Saquon Barkley +550
Ja’Marr Chase +900
Jahmyr Gibbs +1300
Derrick Henry +1400
Justin Jefferson +1400
Puka Nacua +1600
Nico Collins +1600
Bijan Robinson +1800
CeeDee Lamb +2000
Christian McCaffrey +2000
Amon-Ra St. Brown +2500
Tyreek Hill +3500
Brian Thomas Jr. +3500
Malik Nabers +3500
De’Von Achane +3500
Drake London +4000
A.J. Brown +4000
Jonathan Taylor +4200
Kyren Williams +5000
Jayden Daniels +5000
Jaxon Smith-Njigba +5000
Brock Bowers +5000
Ashton Jeanty +5000
Ladd McConkey +6000
🚨 best bets for all 32 #NFL teams! 🚨
I took a look at all 32 NFL teams and picked my 3 best bets for each one, here they are in alphabetical order @GamblingPodcast #BirdGang https://t.co/E4SecBWm8W
— Cody Zeeb (@Husker_Zeeb) July 7, 2025
2025 NFL Best Bets: Offensive Player of the Year Odds, Trends, and Past Winners
Ja’Marr Chase (+900)
Chase hasn’t won this award yet. He finished third in the voting last season, putting up 1,708 receiving yards and catching 17 touchdowns. This Bengals offense is one of, if not my favorite, heading into this season. With Burrow healthy and Chase and Higgins re-signed for the long term, the core of the offense stays in place. They’ve made some changes and updates to the defense, but questions remain about some contracts and just how good they can be. Either way, this offense will be explosive, and like we saw with Josh Allen getting the MVP last year, the voters want to reward the stars of the league. When it comes to the favorites, Chase is the best bet for me.
Christian McCaffrey (+2000)
McCaffrey is just too good a player and talent to pass up at this number. Everyone is disappointed in last season, and that’s understandable. But when we’ve had the chance to see him play at full strength, there aren’t many who can do it like he does. He won the award with a stellar season just two years ago, and he’s still only 29 years old.
When you take a look at this 49ers team, they have the easiest predicted schedule, which is nice for Christian. They’ve also lost a lot, or are missing a lot of their key stars. With Debo gone, Aiyuk is unlikely to play to start the season, and now Ricky Pearsall is already dealing with an injury. They may lean on McCaffery hard and heavy. This isn’t taking him with the #1 fantasy pick or betting him at a short number. At 20/1, it’s worth the shot he still has that explosive Christian McCaffrey in him that we all know.
De’Von Achane (+3500)
As I look down the board for a longer shot to entertain, Achane jumps off the page to me. Like McCaffrey, he’s got amazing explosive potential. Like McCaffrey, the fragile injury risk exists, but we’re hoping for a best-case scenario. Achane burst onto the scene in 2023, putting up 203 rushing yards in his second career game and going over 100 yards in three of the first four games he played.
Last year, he ended the season heating up with two of his final three games going over 120 rushing yards. Like McCaffrey, he is also super explosive when given the ball in the open field via the pass. He was targeted 87 times last season. The Dolphins could be one of the worst teams or one of the best. But if they are a good team, Achane will be a big part of that.
