Best Bet For Tuesday (July 22nd): MLB Predictions

Best Bet For Tuesday (July 22nd): MLB Predictions

We’ve got more interleague action going down in Major League Baseball this week, including the game I’ve targeted for my best bet for tomorrow. For my best bet for Tuesday, July 22nd: MLB Predictions, we’re off to PNC Park in Pittsburgh for an American League Central vs National League Central matchup. Let’s go!

 

 

 

Best Bet For Tuesday (July 22nd): MLB Predictions

Detroit Tigers vs Pittsburgh Pirates

Start Time: 6:40 PM EST

This may be an interleague series, but the American League’s Detroit Tigers and the National League’s Pittsburgh Pirates have already seen each other plenty this season, with four matchups in the books before tomorrow’s game (the Tigers lead the season series 2-1 heading into action on Monday night).

While the Pirates are rotten as usual, with only 39 wins in their first 100 games, the Tigers remain at or near the top of the majors. And that includes on the road, where they are 28-22 as of this writing, the top mark in the majors.

Even taking into account the Pirates’ home field advantage playing in Pittsburgh (worth 0.39 runs per game, second-best all-time in the majors), the Tigers still show up as the play tomorrow, projected to be about a run better than the Pirates. And, as an added bonus, we’re getting Detroit for a decent price on the moneyline on Tuesday.

Best Bet: Detroit ML (-137)

 

Best Bet Overall Record: 251-227 (53%)
Profit (based on $100/bet): -($963.68)
Return on Investment: -2%

 

SGPN Daily Content for July 22nd, 2025

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MMA Daily Best Bet

 

 

Don’t Forget About our Free Picks Pages Too!

NBA PICKS – UPDATED DAILY

COLLEGE BASKETBALL PICKS – THE PICKS POWERHOUSE

NHL PICKS – LET IT SLIDE

SOCCER PICKS – KICK IT ON THE PITCH

NASCAR PICKS – FEEL THE THUNDER

UFC PICKS – TAKE DOWN CORPORATE GAMBLING

 

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