The NFL season is quickly approaching! Mandatory Mini Camps are here, and the Hall-of-Fame game between the Los Angeles Chargers and Detroit Lions takes place at the end of next month. We’re taking a look at all 32 NFL teams and our best bets for each prior to the 2025 season kicking off. The Los Angeles Chargers are up next, so let’s take a look at this edition of the 2025 NFL Best Bets: Los Angeles Chargers.
Jim Harbaugh enters his second season as the Chargers’ head man after going 11-6 in year one. Justin Herbert is back for his sixth season as the Chargers’ quarterback. The team lost Joey Bosa to free agency. On offense, they added running back Najee Harris and brought back wide receiver Mike Williams. They also drafted running back Omarion Hampton in the first round of the NFL Draft.
2025 NFL Best Bets: Los Angeles Chargers
Justin Herbert Over 22.5 Passing Touchdowns (-110)
Herbert got smarter with the football and improved under Harbaugh in year one. He tossed 23 touchdowns last season and has gone over this number in all four seasons he started 15 games or more.
2025 NFL Best Bets: Los Angeles Chargers
Najee Harris Over 525.5 Rushing Yards (-110)
When I went looking for this prop, I fully intended to take the under. I think it’ll be Hampton’s backfield sooner rather than later. However, Najee can survive in a 2-back field all has over 1,000 yards all four seasons of his career. This number is too low.
Omarion Hampton Over 800.5 Rushing Yards (-105)
To my point above, I think Hampton gets a big role early. Especially in a Jim Harbaugh run the ball down your throat system, both of these guys can be highly successful.