The NFL season is quickly approaching! Mandatory Mini Camps are here, and the Hall-of-Fame game between the Los Angeles Chargers and Detroit Lions takes place at the end of next month. We’re taking a look at all 32 NFL teams and our best bets for each prior to the 2025 season kicking off. The Arizona Cardinals are up first, so let’s take a look at this edition of the 2025 NFL Best Bets: Arizona Cardinals.
Jonathan Gannon is back as the Cardinals’ head coach, and Kyler Murray remains the starting quarterback. The Cardinals didn’t suffer any huge free agency losses; defensive tackle Roy Lopez was probably the biggest. Walter Nolen III, the big defensive tackle from Ole Miss, was their first-round pick with the 16th overall selection, replacing the Lopez loss. Pass rusher Josh Sweat was the Cardinals’ biggest free agency addition as they addressed their defense big time.
2025 NFL Best Bets: Arizona Cardinals
Marvin Harrison Jr Over 925.5 Receiving Yards (-110)
His rookie year seemed disappointing, but that’s because expectations were too high. Harrison racked up 885 yards as a rookie, and I expect a big year two breakout from a player we all know is a stud.
2025 NFL Best Bets: Arizona Cardinals
Over 8.5 Wins (-110)
They improved from four wins in 2023 to eight wins in 2024. Jonathan Gannon and company seem to be moving in the right direction, and their division has some teams with questionable rosters in it. They only have to improve by one win to cash this one.
NFC West Winner (+475)
Seattle has undergone big changes to their roster, as have the 49ers. The Rams are always a team that gets there, but doesn’t always win a ton of games. This seems like one of the most open divisions in all of football. At almost 5/1 with a good enough coach and established starting quarterback, it’s worth the bet.
