The final four teams (not the Final Four teams) will look to punch their tickets to the Elite Eight tomorrow as March Madness rolls on. For my best bet for Friday, March 27th: Sweet Sixteen Predictions, we’re off to Capital One Arena in Washington, D.C., for some East Region action. Let’s get this money!
Best Bet For Friday (March 27th): Sweet Sixteen Predictions
#3 Michigan State Spartans vs #2 UConn Huskies
Start Time: 9:45 PM EST
Outside of a #5 seed (the St. John’s Red Storm) besting a #4, the East Region portion of the bracket has gone the way of the chalk, including this matchup, with the #3 seed Michigan State Spartans facing #2, the UConn Huskies. Not only are they seeded close, but KenPom ranks them right beside each other as well, with the Spartans ranked #9 in the nation, and the Huskies #10.
And I agree with KenPom, and I’m predicting an “upset” in this matchup. Michigan State is slightly better than UConn on the offensive end; UConn is slightly better than Michigan State on the defensive end. And, like I did with my Sweet Sixteen play on Thursday, I’m going with offense over defense.
After crunching the numbers, my line is Michigan State -1, so I’ll gladly take the Spartans plus the points tomorrow as my best bet.
Best Bet: Michigan State +2 (-110)
Best Bet Overall 2026 Record: 56-28 (67%)
Profit (based on $100/bet): $1,531.52
Return on Investment: 18%
SGPN Daily Content for March 27th, 2026
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