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Kansas City Chiefs vs. San Francisco 49ers – NFL – Predictions, Betting Lines, Odds and Trends

The top team in the AFC West, the Kansas City Chiefs (4-2), are 3-point favorites against the NFC West-leading San Francisco 49ers (3-3) on Sunday, October 23, 2022 at Levi’s Stadium. A 48.5-point over/under is set for the contest.

Chiefs vs. 49ers Predictions

Chiefs vs. 49ers Odds

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Chiefs and 49ers: Last Three Games

  • The Chiefs have covered the spread once in their last three matchups while putting together a 2-1 record straight-up in those games.
  • Two times in those three games, the final combined score has exceeded the set total.
  • The Chiefs’ last three games have ended with an average of 51 points scored. That’s 2.5 more points than this contest’s over/under.
  • The 49ers are 2-1 against the spread and 2-1 overall in their last three contests.
  • One time in those three games, the final combined score went over the set total.
  • The past three 49ers games averaged 5.8 fewer points (42.7) than this matchup’s point total.

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Chiefs and 49ers: Betting Trends

  • The Chiefs have covered the spread two times this season (2-4-0).
  • In games they have played as 3-point favorites or more, the Chiefs have an ATS record of 1-3.
  • This season, three Chiefs games have gone over the point total.
  • The Chiefs are 3-1 in games they were listed as the moneyline favorite (winning 75% of those games).
  • When they have played as a moneyline favorite with odds of -166 or shorter, the Chiefs have gone 3-1 (75%).
  • The Chiefs have a 62.4% chance to win this game based on the moneyline’s implied probability.
  • The 49ers are 3-3-0 against the spread this year.
  • 49ers games have gone over the total once this season.
  • This is the first time the 49ers will play as underdogs this season.
  • The 49ers have not been a bigger underdog this season than the +140 moneyline set for this game.

Over/Under Trends

  • The Chiefs and their opponents have combined to outscore Sunday’s total (48.5 points) four times this season.
  • There has been just one game featuring the 49ers this season with more combined scoring than Sunday’s over/under of 48.5.
  • Together, the two teams combine for 50.1 points per game, 1.6 points more than the total of 48.5 for this contest.
  • These two teams give up a combined 39.6 points per game, 8.9 points less than this contest’s over/under.
  • This season, the average total for Chiefs games is 51.8 points, 3.3 more than the over/under of 48.5 points for this contest.
  • A difference of 6.7 points separates this contest’s over/under (48.5 points) and the average total points bet in 49ers’ games (41.8 points) this season.

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Chiefs Players to Watch

  • Patrick Mahomes II is the No. 4 fantasy player overall and the No. 4 fantasy QB with 142.7 points (averaging 23.8 per game).
  • Travis Kelce’s 88 total fantasy points (an average of 14.7 per game), are good enough to place him 20th overall and first among TEs.
  • So far this season, Clyde Edwards-Helaire averages 11.6 fantasy points per game on the way to 69.3 total fantasy points. That makes him the 44th-ranked fantasy player overall and the 13th-ranked RB.
  • JuJu Smith-Schuster is the 106th-ranked fantasy player — and the 34th-ranked WR — with 41 fantasy points. He averages 6.8 fantasy points per game.

49ers Players to Watch

  • So far this season, Jimmy Garoppolo is 36th overall among all players and 20th among all QBs with 73.9 fantasy points (14.8 per game).
  • Deebo Samuel has put up total 64.1 fantasy points this year (10.7 per game), which make him the ninth-ranked WR and the 50th-ranked player overall.
  • Jeff Wilson Jr.’s 55 total fantasy points make him the No. 61 fantasy player and No. 19 RB. He averages 9.2 fantasy points per game.
  • Brandon Aiyuk’s fantasy season so far has him ranked 21st among WRs and 75th overall with 50.7 points (8.5 per game).

Where To Watch Chiefs vs. 49ers

*Confirm FuboTV’s schedule of programming for exact games available

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