San Diego Padres vs. San Francisco Giants – MLB – Predictions, Betting Lines, Odds and Trends

The San Diego Padres (89-72) aim to finish off a sweep of a three-game series versus the San Francisco Giants (80-81), at 4:10 PM ET on Wednesday.

The Padres are favored at home (-150) against the Giants (+128). Mike Clevinger (7-7) will start in this one for the San Diego Padres. The San Francisco Giants have yet to tab a starting pitcher for this game. The total in the game is 7.5 total runs.

Padres vs. Giants Predictions

Padres vs. Giants Betting Odds

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Padres vs. Giants Last 10 Games Betting Performance


  • San Diego was favored on the moneyline in eight of its last 10 games, and went 6-2 in those matchups.
  • Over their last 10 matchups (all had set totals), the Padres combined with their opponents to hit the over on the total four times.
  • San Diego has gone 6-4-0 against the spread over its past 10 games.

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  • San Francisco has played as the underdog in four of its past 10 games and has won one of those contests.
  • When it comes to hitting the over, the Giants and their opponents are 6-4-0 in their last 10 games with a total.
  • San Francisco has a record of 5-5-0 ATS over its last 10 games.

Padres vs. Giants Starting Pitcher Betting Trends

Projected starter: Mike Clevinger

  • The Padres have a 13-9-0 ATS record in Clevinger’s 22 starts that had a set spread.
  • The Padres have an 11-4 record in Clevinger’s 15 starts this season when they were the moneyline favorite.
  • Clevinger’s team has put together a 15-7 record over his 22 starts.
  • Clevinger has had 22 starts that oddsmakers set a total for this season, and 13 of those games hit the over.

Padres Batting Leaders

  • Manny Machado leads the Padres in home runs (32), runs batted in (102) and has accumulated a team-best batting average of .296.
  • Machado ranks 15th in homers and seventh in RBI among all hitters in MLB.
  • Juan Soto has 25 doubles, two triples, 27 home runs and 135 walks while hitting .244.
  • Among all MLB hitters, Soto ranks 30th in homers and 97th in RBI.
  • Josh Bell is hitting .266 with 29 doubles, three triples, 17 home runs and 81 walks.
  • Jake Cronenworth has 30 doubles, four triples, 17 home runs and 70 walks while batting .240.
  • Cronenworth heads into this game on a five-game hitting streak. In his last five games he is hitting .333 with three doubles, a home run, two walks and four RBI.

Giants Batting Leaders

  • Wilmer Flores is batting .229 for San Francisco with a team-high 71 RBI.
  • Flores ranks 72nd in home runs and 64th in RBI among all hitters in the big leagues.
  • Thairo Estrada leads San Francisco in batting with a .260 average while slugging 14 homers and driving in 62 runs.
  • Among all major league batters, Estrada ranks 126th in homers and 97th in RBI.
  • Joc Pederson’s 23 home runs lead all San Francisco hitters, and he’s slugging .521.
  • Mike Yastrzemski has collected 102 hits this season and has an OBP of .303. He’s slugging .387 on the year.

Where To Watch Padres vs. Giants

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