San Diego Padres vs. St. Louis Cardinals – MLB – Predictions, Betting Lines, Odds and Trends

Brendan Donovan has 99 hits, and will try to notch his 100th when his St. Louis Cardinals (87-62) play the San Diego Padres (82-66) at 9:40 PM ET on Wednesday.

The Padres are favored (-124 on the moneyline to win) when they host the Cardinals (+104). The Padres will give the ball to Blake Snell (7-9) versus the Cardinals and Miles Mikolas (11-12). The over/under for this game is set at 7.5.

Padres vs. Cardinals Predictions

Padres vs. Cardinals Betting Odds

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Padres vs. Cardinals Last 10 Games Betting Performance


  • San Diego has a 3-1 record across the four games it was favored on the moneyline in its last 10 matchups.
  • In their last 10 outings, the Padres and their opponents combined to go over the run total four times (all 10 of the games had set totals).
  • San Diego is 6-4-0 against the spread over its past 10 games.

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  • Over the past 10 games, St. Louis has been the underdog twice and split those games 1-1.
  • In their last 10 games with a total, the Cardinals and their opponents have combined to hit the over three times.
  • St. Louis has a record of 3-7-0 ATS over its last 10 games.

Padres vs. Cardinals Starting Pitcher Betting Trends

Projected starter: Blake Snell

  • When Snell starts, the Padres are 8-14-0 against the spread.
  • The Padres are 7-9 in Snell’s 16 starts this season with San Diego as the moneyline favorite.
  • Snell’s team is 8-14 in his 22 starts.
  • Snell’s starts hit the over on the run total nine times in 22 games with a set total this season.

Projected starter: Miles Mikolas

  • Mikolas and his team are 17-14-0 ATS this season when he starts.
  • His team has won 50% of his starts when they are underdogs on the moneyline (5-5).
  • In games Mikolas has started, his team is 17-13.
  • Games Mikolas has started this season hit the over 13 times in 31 chances.

Padres Batting Leaders

  • Manny Machado has racked up a team-high batting average of .297, and paces the Padres in home runs (29) and runs batted in (93).
  • Among all hitters in MLB action, Machado’s home run total ranks 16th and his RBI tally ranks 13th.
  • Machado enters this game on a four-game hitting streak. During his last five outings he is batting .250 with a home run, a walk and three RBI.
  • Juan Soto is hitting .242 with 22 doubles, two triples, 25 home runs and 126 walks.
  • Soto currently ranks 32nd in home runs and 84th in RBI in the bigs.
  • Soto brings a two-game hitting streak into this game. During his last five outings he is batting .368 with two doubles, a home run, three walks and six RBI.
  • Josh Bell has 29 doubles, three triples, 17 home runs and 72 walks while batting .274.
  • Brandon Drury is hitting .263 with 28 doubles, two triples, 27 home runs and 34 walks.

Cardinals Batting Leaders

  • Paul Goldschmidt is batting .322 with 35 home runs and 112 RBI. All three of those stats rank first among St. Louis hitters this season.
  • Among all hitters in MLB, Goldschmidt ranks seventh in homers and fourth in RBI.
  • Nolan Arenado has 155 hits and an OBP of .359 to go with a slugging percentage of .542 this season.
  • Among all MLB hitters, Arenado ranks 16th in home runs and eighth in RBI.
  • Tommy Edman is slashing .269/.325/.408 this season for the Cardinals.
  • Donovan has collected 99 hits this season and has an OBP of .390. He’s slugging .370 on the year.

Where To Watch Padres vs. Cardinals

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