St. Louis Cardinals vs. Washington Nationals – MLB – Predictions, Betting Lines, Odds and Trends

The St. Louis Cardinals (52-47) and Washington Nationals (34-66) clash in the first of a three-game series on Friday at Nationals Park, at 7:05 PM ET. The Cardinals are coming off a series split with the Blue Jays, and the Nationals a series win over the Dodgers.

The Cardinals are favored (-200 on the moneyline) when they visit the Nationals (+170). The matchup on the mound for this contest is set with the St. Louis Cardinals looking to Miles Mikolas (7-8), and Anibal Sanchez (0-2) getting the nod for the Washington Nationals. The contest has a set total of 9.

Cardinals vs. Nationals Predictions

Cardinals vs. Nationals Betting Odds

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Cardinals vs. Nationals Last 10 Games Betting Performance


  • St. Louis was favored on the moneyline in five of its last 10 games, and went 3-2 in those matchups.
  • Over their last 10 outings, the Cardinals and their opponents combined to go over the run total six times (all 10 games had set totals).
  • St. Louis’ record against the spread is 6-4-0 over its past 10 games.


  • In 10 games as the underdog over the last 10 matchups, Washington has a record of 4-6.
  • In their last 10 games with a total, the Nationals and their opponents have failed to hit the over five times.
  • Washington has won five of its last 10 games against the spread.

Cardinals vs. Nationals Starting Pitcher Betting Trends

Projected starter: Miles Mikolas

  • The Cardinals are 12-8-0 against the spread when Mikolas starts.
  • The Cardinals are 6-4 in Mikolas’ 10 starts this season with St. Louis as the moneyline favorite.
  • Mikolas’ team has an 11-9 record over his 20 starts.
  • Mikolas has had 20 starts that oddsmakers set a total for this season, and nine of those games finished over the total.

Projected starter: Aníbal Sánchez

  • Sánchez has a record of 1-1-0 ATS in two starts with a spread this season.
  • His team is 0-2 this season when he starts and they’re underdogs on the moneyline.
  • Sánchez’s team is 0-2 when he starts this season.
  • In the two games with a total started by Sánchez this season, the teams did not hit the over.

Cardinals Batting Leaders

  • Tommy Edman has driven in a team-high 35 runs batted in.
  • Among hitters in MLB, Edman ranks 166th in homers and 129th in RBI.
  • Dylan Carlson’s .259 batting average is a team-high mark.
  • Carlson currently ranks 185th in homers and 177th in RBI in the bigs.
  • Carlson has safely hit in two games in a row. In his last five games he is hitting .286 with three doubles, a home run and three RBI.
  • Brendan Donovan is batting .281 with 14 doubles, a triple, two home runs and 36 walks.
  • Albert Pujols is batting .241 with eight doubles, seven home runs and 17 walks.
  • Pujols brings a five-game hitting streak into this matchup. In his last five games he is batting .471 with two doubles, a home run, two walks and four RBI.

Nationals Batting Leaders

  • Juan Soto is batting .237 this season with a team-high 20 home runs.
  • Among all batters in the big leagues, Soto’s home run total is 17th, and his RBI total is 64th.
  • Josh Bell leads Washington in batting average (.305) and runs batted in (53) this season while also slugging 13 homers.
  • Bell currently is 60th in home runs and 29th in RBI in the major leagues.
  • Nelson Cruz is slashing .231/.317/.347 this season for the Nationals.
  • Cesar Hernandez has 95 hits and an OBP of .306 to go with a slugging percentage of .307 this season.
  • Hernandez brings a three-game hitting streak into this matchup. During his last five outings he is batting .222 with a double, three walks and an RBI.

Where To Watch Cardinals vs. Nationals

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