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San Diego Padres vs. San Francisco Giants – MLB – Predictions, Betting Lines, Odds and Trends

The San Diego Padres (47-36) and San Francisco Giants (41-39) square off on Thursday at 9:40 PM ET, opening a four-game series at PETCO Park.

The Giants are an underdog away (+113) at the Padres (-134). The matchup on the mound for this contest is set with the San Diego Padres looking to Joe Musgrove (8-2), and Logan Webb (7-3) answering the bell for the San Francisco Giants. The over/under for the game is 6.5 total runs.

Padres vs. Giants Predictions

Padres vs. Giants Betting Odds

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Padres vs. Giants Last 10 Games Betting Performance


  • San Diego played as the moneyline favorite in six of its last 10 games, and finished 1-5 in those matchups.
  • In their last 10 matchups (all had set totals), the Padres combined with their opponents to go over the run total five times.
  • San Diego has a 2-8-0 record against the spread over its past 10 games.


  • San Francisco is not favored for the first time in a while, as it has not been the underdog in its last 10 games.
  • In their last 10 games with a total, the Giants and their opponents have combined to hit the over six times.
  • San Francisco has a record of 2-8-0 ATS over its last 10 games.
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Padres vs. Giants Starting Pitcher Betting Trends

Projected starter: Joe Musgrove

  • The Padres are 10-4-0 ATS in Musgrove’s 14 starts with a set spread.
  • The Padres have been favored on the moneyline in 10 of Musgrove’s starts this season, and they went 8-2 in those games.
  • Musgrove’s team has an 11-3 record in his starts this season.
  • Musgrove’s starts went over the run total seven times in 14 games with a set total this season.

Projected starter: Logan Webb

  • Webb’s team is 8-8-0 against the spread in his starts this season.
  • His team has been defeated in each of the four games he’s started as the moneyline underdog.
  • Webb’s team is 10-6 when he starts this season.
  • In games Webb has started this season, the teams are 9-8-0 at hitting the over.

Padres Batting Leaders

  • Manny Machado has accumulated a team-high batting average of .316, and paces the Padres in home runs (12) and runs batted in (46).
  • Machado’s home runs rank 53rd in MLB and he ranks 26th in RBI in MLB.
  • Jurickson Profar is hitting .244 with 20 doubles, two triples, eight home runs and 46 walks.
  • Among all MLB hitters, Profar ranks 107th in homers and 64th in RBI.
  • Jake Cronenworth is batting .240 with 20 doubles, two triples, seven home runs and 36 walks.
  • Eric Hosmer is batting .269 with 14 doubles, six home runs and 24 walks.

Giants Batting Leaders

  • Wilmer Flores is batting .246 for San Francisco with a team-high 41 RBI.
  • Among all hitters in the big leagues, Flores ranks 90th in homers and 50th in RBI.
  • Flores has safely hit in two games in a row. In his last five games he is batting .300 with a double, four walks and an RBI.
  • Joc Pederson is batting .269 this season with a team-high 17 home runs and 41 RBI.
  • Pederson is 16th in home runs and 50th in RBI among all major league batters this season.
  • Mike Yastrzemski is slashing .231/.335/.403 this season for the Giants.
  • Darin Ruf has collected 50 hits this season and has an OBP of .338. He’s slugging .362 on the year.
  • Ruf has safely hit in two games in a row. During his last five outings he is hitting .364 with two doubles, a home run, a walk and four RBI.

Where To Watch Padres vs. Giants

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