Cleveland Guardians vs. Kansas City Royals – MLB – Predictions, Betting Lines, Odds and Trends

The Cleveland Guardians are facing the Kansas City Royals to begin the MLB season on Thursday. The matchup starts at 4:10 PM ET at Kauffman Stadium.

The Guardians are favored (-128 moneyline odds to win) when they visit the Royals (+108). The Guardians will give the ball to Shane Bieber versus the Royals and Zack Greinke. The matchup has an over/under of 8.5 total runs.

Guardians vs. Royals Predictions

Guardians vs. Royals Betting Odds

Guardians vs Royals Betting Information
Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Spread Favorite Spread Odds Underdog Spread Odds
Guardians -128 +108 8.5 -105 -115 -1.5 +129 -154

Guardians vs. Royals Hitting Splits 2021


  • The Guardians averaged 1.2 home runs per game when playing on the road last season (101 total in road contests).
  • The Guardians slugged .403 with 3.0 extra-base hits per game in road contests.
  • The club averaged 8.1 hits per game and batted .238 on the road last season.
  • The Guardians scored an average of 4.6 runs per game on the road.
  • The Guardians averaged 2.8 walks per game with an on-base percentage of .403 on the road.
  • On the road last season the club averaged 8.9 strikeouts per game.


  • In 81 games at home last season, they hit 76 homers, an average of 0.9 per contest.
  • In 81 home games last season, they had a .409 SLG with 230 hits going for extra bases.
  • They averaged 8.7 base hits per game and hit .261 as a team at home last season.
  • They scored 4.7 runs per game last season at home.
  • In 81 home games last season, they had a team OBP of .322 with 2.8 walks drawn per contest.
  • They struck out 7.4 times per game in 81 home games last season.

Guardians vs. Royals Starting Pitcher Betting Trends

Projected starter: Shane Bieber

  • Last season Bieber and his team went 7-6-0 against the spread in games he pitched.
  • Bieber and his team finished 9-3 in the 12 games he pitched when they were favored on the moneyline a season ago.
  • He made 16 appearances last year and his team went 11-5 in those games.

Projected starter: Zack Greinke

  • In games Greinke pitched with a spread last season, his team was 13-11-0 ATS.
  • Greinke and his team won as underdogs in three of his six appearances last season with a moneyline.
  • The 38-year-old made 29 appearances last year and his team went 18-13 in those games.
  • When he pitched last season, the teams combined to hit the over 16 times in 29 chances

Guardians Batting Leaders

  • Jose Ramirez had 36 home runs and 103 runs batted in last season.
  • Myles Straw hit .271 with 29 doubles, a triple, four home runs and 67 walks.
  • Amed Rosario had a batting average of .282 with 155 total hits last season.
  • Franmil Reyes hit .254 with 18 doubles, two triples, 30 home runs and 43 walks.

Guardians Batting Leaders

  • Whit Merrifield finished last season with 10 home runs, 74 RBI and a batting average of .277.
  • Salvador Perez is batting .273 last season with a team-high 48 home runs and 121 RBI.
  • Carlos Santana finished with a .214 average, 19 home runs and 69 RBI last season.
  • Nicky Lopez posted a .300 average with 43 RBI.

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