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San Francisco 49ers vs. Jacksonville Jaguars NFL Betting Preview for Week 11

Oddsmakers give the San Francisco 49ers (4-5) the advantage on Sunday, November 21, 2021 against the Jacksonville Jaguars (2-7). San Francisco is favored by 6.5 points. The contest has an over/under of 45 points.

49ers Vs. Jaguars Odds

49ers vs Jaguars Betting Information
Favorite Spread Favorite Spread Odds Underdog Spread Odds Total Over Total Odds Under Total Odds Favorite Moneyline Underdog Moneyline
49ers -6.5 -109 -111 45 -110 -110 -279 +225

49ers and Jaguars: Last Three Games

  • San Francisco is 2-1-0 against the spread in its past three games, and has a 2-1 straight-up record in those matchups.
  • The final combined score of the last three 49ers games has surpassed the set total two times.
  • The past three 49ers games averaged 45.0 points, which equals this matchup’s point total.
  • Jacksonville is 2-1-0 against the spread over its last three games, and has a 1-2 straight-up record in those matchups.
  • The Jaguars and their opponents did not hit the over in any of those games.
  • The last three Jaguars games averaged 47.0 total points, 2.0 more points than this matchup’s over/under.

49ers and Jaguars: Betting Trends

  • San Francisco has covered the spread three times over nine games with a set spread.
  • The 49ers have not covered the spread (0-1) when playing as at least 6.5-point favorites.
  • San Francisco games have finished with a final combined score above the over/under five times this season.
  • The 49ers have won three of the seven games they were the moneyline favorite this season (42.9%).
  • San Francisco has played as a moneyline favorite of -279 or shorter in just one game this season, which they won.
  • Based on this game’s moneyline, the 49ers’ implied win probability is 73.6%.
  • Jacksonville has gone 4-5-0 against the spread this year.
  • In games they have played as 6.5-point underdogs or more, the Jaguars have an ATS record of 3-1.
  • Games involving Jacksonville have hit the over twice this year.
  • This season, the Jaguars have been the underdog eight times and won two of those games.
  • Jacksonville is 1-3 this season when entering a game as the underdog by +225 or more on the moneyline.


Over/Under Trends

  • This season, San Francisco games have hit the over on this game’s 45-point total six times.
  • This season, four of Jacksonville’s games have ended with a score higher than 45 points.
  • The 49ers average 24.0 points per game against the Jaguars’ 16.6, totaling 4.4 points under the matchup’s total of 45.
  • This matchup’s over/under is 4.4 fewer points than the 49.4 these two teams combine to give up per game in 2020.
  • The 49ers have seen a 46.9 average over/under in their games this season, 1.9 points more than the over/under in this contest.
  • Jaguars’ games have a total points bet of 47.2 points this season, 2.2 points more than the over/under for this contest.

49ers Players to Watch

  • Deebo Samuel is the 24th-best fantasy player overall this season and the second-best fantasy receiver with 141.7 fantasy points (15.7 per game).
  • Jimmy Garoppolo’s 124.8 total fantasy points (an average of 13.9 per game), are good enough to rank him 33rd overall and 22nd among quarterbacks.
  • Elijah Mitchell is 78th overall and 23rd among running backs after scoring 81.3 fantasy points (averaging 9.0 per game) so far this season.
  • Trey Lance is the 156th-ranked fantasy player — and the 35th-ranked quarterback — with 47.5 fantasy points. He averages 5.3 fantasy points per game.

Jaguars Players to Watch

  • So far this season, Trevor Lawrence is 40th overall among all players and 25th among all quarterbacks with 116.2 fantasy points (12.9 per game).
  • James Robinson has collected 105.9 fantasy points this year (11.8 per game), good enough to rank him 15th among running backs and 50th overall in league-wide fantasy standings.
  • Marvin Jones Jr. averages 6.8 fantasy points per game on the way to 61.4 total fantasy points. That makes him the 116th-ranked fantasy player overall and the 40th-ranked receiver.
  • Jamal Agnew’s fantasy season so far has him ranked 51st among receivers and 148th overall with 50.0 points (5.6 per game).

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